le 2 octobre/October&nbsp;2023

	The common shares of Safe Supply Streaming Co Ltd. (SPLY)&nbsp;previously listed&nbsp;as Origin Therapeutics Holdings Inc. (ORIG) have been approved for listing on the CSE.

	Listing and disclosure documents will be available at&nbsp;www.thecse.com&nbsp;on the trading date.

	Safe Supply Streaming Co. Ltd. is investing in and incubating companies at the forefront of the third wave of drug policy reform. As jurisdictions around the world move to decriminalize, regulate and legalize drugs, Safe Supply is investing in the infrastructure necessary to support the transition. From developing the facilities to analyze, manufacture and distribute psychoactive compounds, to investing in the research and to harness the potential, and minimize the harm, of these medicines, to constructing the clinical infrastructure to ensure safe and responsible access and treatment.

	________________________

	Les actions ordinaires de Safe Supply Streaming Co Ltd. (SPLY), précédemment cotées sous le nom d'Origin Therapeutics Holdings Inc. (ORIG), ont été approuvées pour leur inscription au CSE.

	Les documents de cotation et d'information seront disponibles sur www.thecse.com à la date de négociation.

	Safe Supply Streaming Co. Ltd. investit et incube des entreprises à l’avant-garde de la troisième vague de réforme de la politique en matière de drogues. Alors que les juridictions du monde entier s’efforcent de décriminaliser, réglementer et légaliser les drogues, Safe Supply investit dans l’infrastructure nécessaire pour soutenir la transition. Du développement des installations pour analyser, fabriquer et distribuer des composés psychoactifs, à l'investissement dans la recherche et à l'exploitation du potentiel et à minimiser les dommages de ces médicaments, à la construction de l'infrastructure clinique pour garantir un accès et un traitement sûrs et responsables.
<table border="1" cellpadding="0" cellspacing="0" >
<tbody>
<tr>
<td >

					Issuer/Émetteur :
</td>
<td >

					Safe Supply Streaming Co Ltd.
</td>
</tr>
<tr>
<td >

					Security Type/Titre :
</td>
<td >

					Common&nbsp;Shares/Actions&nbsp;ordinaires
</td>
</tr>
<tr>
<td >

					Symbol(s)/Symbole(s) :
</td>
<td >

					SPLY
</td>
</tr>
<tr>
<td >

					Number of securities issued and outstanding/&nbsp;Titres&nbsp;émis&nbsp;et en circulation :
</td>
<td >

					70 217 750
</td>
</tr>
<tr>
<td >

					Number of Securities reserved for issuance/&nbsp;Titres&nbsp;réservés&nbsp;pour&nbsp;émission :
</td>
<td >

					8 809 750
</td>
</tr>
<tr>
<td >

					CSE Sector/Catégorie :
</td>
<td >

					Diversified Industries/Sociétés diversifiées
</td>
</tr>
<tr>
<td >

					CUSIP :
</td>
<td >

					78643W 10 8
</td>
</tr>
<tr>
<td >

					ISIN :
</td>
<td >

					CA 78643W 10 8 6
</td>
</tr>
<tr>
<td >

					OLD&nbsp;CUSIP/ISIN :
</td>
<td >

					68622H107/CA68622H1073
</td>
</tr>
<tr>
<td >

					Boardlot/Quotité :
</td>
<td >

					500
</td>
</tr>
<tr>
<td >

					Consolidation:
</td>
<td >

					4 Old for 1 New/4 Ancien&nbsp;pour 1 Nouveaux
</td>
</tr>
<tr>
<td >

					Trading&nbsp;Currency/Monnaie&nbsp;de&nbsp;négociation :
</td>
<td >

					CDN$
</td>
</tr>
<tr>
<td >

					Trading Date/Date de&nbsp;negociation :
</td>
<td >

					le 3&nbsp;OCT&nbsp;2023
</td>
</tr>
<tr>
<td >

					Other Exchanges/Autres&nbsp;marches :
</td>
<td >

					N/A
</td>
</tr>
<tr>
<td >

					Fiscal Year&nbsp;end /Clôture&nbsp;de&nbsp;l'exercice&nbsp;financier :
</td>
<td >

					le 30 SEPT
</td>
</tr>
<tr>
<td >

					Transfer Agent/Agent des&nbsp;transferts :
</td>
<td >

					Olympia Trust Company
</td>
</tr>
</tbody>
</table>

	The Exchange is accepting Market Maker applications for SPLY. Please email:&nbsp;<a href="mailto:TRADING@THECSE.COM">Trading@theCSE.com</a>

	If you have any questions or require further information please contact Listings at (416) 367-7340 or E-mail:&nbsp;<a href="mailto:Listings@thecse.com">Listings@thecse.com</a>

	Pour&nbsp;toute&nbsp;question, pour&nbsp;obtenir&nbsp;de&nbsp;l’information&nbsp;supplémentaire&nbsp;veuillez&nbsp;communiquer&nbsp;avec&nbsp;le service des inscriptions au 416 367-7340 ou par&nbsp;courriel&nbsp;à&nbsp;l’adresse:&nbsp;<a href="mailto:Listings@thecse.com">Listings@thecse.com</a>

Safe Supply Streaming Co Ltd.

2023-1002 - Fundamental Change - Origin Therapeutics Holdings Inc./Safe Supply Streaming Co Ltd.

CSE25™

CSE Composite Index®

In this series, we delve deep into the experiences of CSE listed companies, exploring their past successes and future opportunities.

CSE Issuer Spotlight

**Follow us** for the **latest news** from the CSE

 The CSE provides a modern and efficient alternative for companies looking to access the Canadian public capital markets.

The Canadian Securities Exchange (CSE)

Learn how we streamline issuer regulation through enhanced disclosure, practical and effective regulatory oversight, and modern technology.

Listing on the CSE

Learn more about the companies we list and how to get started trading on the CSE.

Investing in Listed Companies

Learn how we lower costs, reduce complexity, and provide market making opportunities for the dealer community.

Trading on the CSE

Whether you’re an investor, business leader, or simply looking to learn more, start your journey with the CSE here.

Get Started

From announcements and market updates to in-depth interviews with company leaders - stay informed with the latest from the CSE.

Latest from the CSE

Discover newly listed companies on the CSE through our series of bite-sized interviews with company leaders.

Get to know our latest listings

Listed Company News

Market Activity

List with the CSE

Find a home for your next big idea.

Frequently Asked Questions

How does being listed on the CSE affect me as a shareholder?

Where do I get information and trade CSE listed securities?

Where can I find an RSS feed for listed company news?

Where is the CSE recognized?

Upcoming Events

join the list

Join our mailing list to receive buy-in notifications

The CSE provides a superior exchange experience by investing in our customers’ success with innovation, dedication, and passion.

Where innovation, passion, and trust intersect

We strive to be the most innovative exchange in Canada. We aim to offer unlimited global access and a customized client-centric experience while delivering the lowest cost of public capital. 

We are Canada's entrepreneurial exchange

The most searched CSE listed companies on thecse.com

Recent Quotes

Get the latest regulatory announcements from the CSE concerning its Listings Policies, Trading Rules and functionality and other important industry developments.

Notices

Get the latest information about new CSE listings, the appointment of Market Makers, market events, and other news.

Bulletins

Stay informed with CSE listed company news, providing transparency and accountability to shareholders and the public.

Company News

Stay Informed

The **total volume** traded on the CSE today is

Connect with our professionals and listing experts at industry events and conferences.